What do you mean "Non-Sedative?2
Let's be clear: Sedation is everything when it comes to antihistamines. The one that offers non-sedative allergy symptom relief, that's the one you need to take seriously. Picture this: non-sedative relief means staying on point during that big meeting, keeping your plans intact, and no dozing off halfway through the day, all while tackling allergy symptoms.3
Sounds like a dream come true for anyone battling allergies, right?
Achieving Clear Brain Function Without Sedation
The blood-brain barrier prevents certain things from entering, so your brain cells can keep functioning at their best without any unwanted interference. Our formula respects this boundary, ensuring your brain stays safe and uncompromised.2
MORE ON 0% BRAIN INTERFERENCE2
Effect on ability to drive and use machines:The effects of this medicine on a person's ability to drive and machines were not assessed as part of its registration.1
Why Telfast®?
All the relief, without sedation, that's why.
24 Hours1
That's right, Telfast® provides up to 24 hours of non-drowsy relief without crossing the blood-brain barrier, so you can enjoy your day to the fullest knowing you're covered right around the clock! That said, you should still use the old allergy excuse if you don't want to go somewhere... we won't tell.1
The science behind non-drowsy relief since 1996.4
Telfast® first approved in 1996, offers efficacy that is similar to that of second-generation antihistamines without the risk of blocking cardiac delayed rectifier potassium currents.
Telfast® does not cross the blood-brain barrier and is poorly lipid-soluble. Telfast® is a non-sedating oral antihistamine.Telfast®'s active ingredient, fexofenadine, was engineered specifically to remain outside the centralnervous system.4This innovation allows it to work directly on allergy symptoms without affecting your brain. As aresult, Telfast® offers effective symptom relief that keeps you alert and ready to live life fully.1
References
- Egyptian Drug Authority (EDA), Telfast. Leaflet approval date: 25/06/2023.
- Ansotegui IJ, Bousquet J, Canonica GW, et al. Why fexofenadine is considered as a truly non-sedating antihistamine with no brain penetration: a systematic review. Current Medical Research and Opinion. 2024;40(8):1297-309.
- Cauwenberge V, Juniper, Star Study Investigating Group. Comparison of the efficacy, safety and quality of life provided by fexofenadine hydrochloride 120 mg, loratadine 10 mg and placebo administered once daily for the treatment of seasonal allergic rhinitis. Clinical & Experimental Allergy. 2000;30(6):891-9.
- Howarth PH, Stern MA, Roi L, Reynolds R, Bousquet J. Double-blind, placebo-controlled study comparing the efficacy and safety of fexofenadine hydrochloride (120 and 180 mg once daily) and cetirizine in seasonal allergic rhinitis. Journal of allergy and clinical immunology. 1999;104(5):927-33.